DISEASES

Disease-gene associations mined from literature

Literature associating TRH and septooptic dysplasia

TRH [ENSP00000303452]

Pro-thyrotropin-releasing hormone; As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.

Synonyms:  TRH,  D6RFM1,  P20396,  D6RFM1p,  hD6RFM1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM