DISEASES

Disease-gene associations mined from literature

Literature associating HEXIM2 and retinitis pigmentosa 44

HEXIM2 [ENSP00000302276]

Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Synonyms:  HEXIM2,  HEXIM2p,  hHEXIM2,  K7EIM4,  K7EJA3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM