DISEASES

Disease-gene associations mined from literature

Literature associating TRIM35 and hypotrichosis-lymphedema-telangiectasia-renal defect syndrome

TRIM35 [ENSP00000301924]

Tripartite motif-containing protein 35; Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth . Involved in the cell death mechanism (By similarity).

Synonyms:  TRIM35,  TRIM35p,  hTRIM35,  E5RGB3,  H0YBF3 ...

Linkouts:  STRING  Pharos  UniProt