Literature associating CLPX and relapsing fever
CLPX [ENSP00000300107]
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP . Targets specific substrates for degradation by the Clp complex . Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure . ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5- aminolevulinate (ALA) synthesis, the first step in heme biosynthesis . Important for efficient erythropoiesis through upregulation of heme biosynthesis . ECO:0000269|PubMed:22841477, ECO:0000269|PubMed:25957689,
Synonyms: CLPX, A0A024R5X7, H0YK07, H0YM48, O76031 ...