DISEASES

Disease-gene associations mined from literature

Literature associating ABCB8 and intestinal tuberculosis

ABCB8 [ENSP00000297504]

Mitochondrial potassium channel ATP-binding subunit; ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane . Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) . Plays a role in mitochondrial iron transport . Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity).

Synonyms:  ABCB8,  ABCB8p,  hABCB8,  C9JA03,  C9JTY4 ...

Linkouts:  STRING  Pharos  UniProt