DISEASES

Disease-gene associations mined from literature

Literature associating ORC5 and Meier-Gorlin syndrome

ORC5 [ENSP00000297431]

Origin recognition complex subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication; Belongs to the ORC5 family.

Synonyms:  ORC5,  ORC5p,  hORC5,  A4D0P7,  G3V0H0 ...

Linkouts:  STRING  Pharos  UniProt