Literature associating H2AC1 and spermatogenic failure 9
H2AC1 [ENSP00000297012]
Histone H2A type 1-A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: H2AC1, H2AC1p, hH2AC1, HIST1H2AA, Q96QV6 ...