DISEASES

Disease-gene associations mined from literature

Literature associating ADH5 and focal dermal hypoplasia

ADH5 [ENSP00000296412]

Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione . Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate . Class-III ADH is remarkably ineffective in oxidizing ethanol ; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

Synonyms:  ADH5,  ADH5p,  hADH5,  D6R9G2,  D6RAY0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM