DISEASES

Disease-gene associations mined from literature

Literature associating ARHGAP15 and Meier-Gorlin syndrome 2

ARHGAP15 [ENSP00000295095]

Rho GTPase-activating protein 15; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.

Synonyms:  ARHGAP15,  B8ZZK0,  H7BZM0,  Q53QZ3,  B8ZZK0p ...

Linkouts:  STRING  Pharos  UniProt  OMIM