DISEASES

Disease-gene associations mined from literature

Literature associating AQP5 and keratoconjunctivitis sicca

AQP5 [ENSP00000293599]

Aquaporin-5; Forms a water-specific channel (PubMed:8621489, PubMed:18768791). Plays an important role in fluid secretion in salivary glands (By similarity). Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells . Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity). ECO:0000269|PubMed:16571723, ECO:0000269|PubMed:18768791,

Synonyms:  AQP5,  AQP5p,  hAQP5,  P55064,  P55064p ...

Linkouts:  STRING  Pharos  UniProt  OMIM