Literature associating U2AF1 and acute megakaryocytic leukemia
U2AF1 [ENSP00000291552]
Splicing factor U2AF 35 kDa subunit; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Synonyms: U2AF1, U2AF1p, hU2AF1, A0A1B0GW87, Q01081 ...