DISEASES

Disease-gene associations mined from literature

Literature associating CALM3 and long QT syndrome

CALM3 [ENSP00000291295]

Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis . Mediates calcium-dependent inactivation of CACNA1C . Positively regulates calcium-activated potassium channel activity of KCNN2 . ECO:0000269|PubMed:23893133, ECO:0000269|PubMed:26969752,

Synonyms:  CALM3,  CALM3p,  hCALM3,  B4DJ51,  CALM1 ...

Linkouts:  STRING  Pharos  UniProt