DISEASES

Disease-gene associations mined from literature

Literature associating CFAP298 and exophthalmos

CFAP298 [ENSP00000290155]

Cilia- and flagella-associated protein 298; Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly . Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity); Belongs to the CFAP298 family.

Synonyms:  CFAP298,  CFAP298p,  hCFAP298,  C9J818,  C9JX57 ...

Linkouts:  STRING  Pharos  UniProt