DISEASES

Disease-gene associations mined from literature

Literature associating UBP1 and mixed glioma

UBP1 [ENSP00000283629]

Upstream-binding protein 1; Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA- box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box; Belongs to the grh/CP2 family. CP2 subfamily.

Synonyms:  UBP1,  UBP1p,  hUBP1,  A0A024R2J0,  A0A024R2L0 ...

Linkouts:  STRING  Pharos  UniProt