DISEASES

Disease-gene associations mined from literature

Literature associating CD96 and hydrolethalus syndrome

CD96 [ENSP00000283285]

T-cell surface protein tactile; May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.

Synonyms:  CD96,  CD96p,  hCD96,  E9PEJ1,  F8WDV3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM