DISEASES

Disease-gene associations mined from literature

Literature associating TCF7L1 and anogenital venereal wart

TCF7L1 [ENSP00000282111]

Transcription factor 7-like 1; Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Synonyms:  TCF7L1,  TCF7L1p,  hTCF7L1,  C9JPE3,  Q9HCS4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM