DISEASES

Disease-gene associations mined from literature

Literature associating HIKESHI and optic atrophy 7

HIKESHI [ENSP00000278483]

Protein Hikeshi; Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin- dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus; Belongs to the OPI10 family.

Synonyms:  HIKESHI,  A0A087WYW7,  E9PJB2,  E9PPG8,  Q53FT3 ...

Linkouts:  STRING  Pharos  UniProt