DISEASES

Disease-gene associations mined from literature

Literature associating SERPING1 and epiglottitis

SERPING1 [ENSP00000278407]

Plasma protease C1 inhibitor; Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.

Synonyms:  SERPING1,  A0A087WUD9,  A0A348GSH7,  B5MCB9,  C9JZJ9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM