Literature associating TNFRSF10B and placenta accreta
TNFRSF10B [ENSP00000276431]
Tumor necrosis factor receptor superfamily member 10B; Receptor for the cytotoxic ligand TNFSF10/TRAIL . The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Synonyms: TNFRSF10B, E9PBT3, O14763, E9PBT3p, hE9PBT3 ...