DISEASES

Disease-gene associations mined from literature

Literature associating FTH1 and hemochromatosis type 1

FTH1 [ENSP00000273550]

Ferritin heavy chain, N-terminally processed; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). ; Belongs to the ferritin family.

Synonyms:  FTH1,  FTH1p,  hFTH1,  A0A024R525,  E9PK45 ...

Linkouts:  STRING  Pharos  UniProt  OMIM