DISEASES

Disease-gene associations mined from literature

Literature associating ECSIT and dental pulp disease

ECSIT [ENSP00000270517]

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family.

Synonyms:  ECSIT,  J3KTF5,  K7EIK2,  K7EJG5,  K7EJI1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM