Literature associating CBX8 and DOID:0040084
CBX8 [ENSP00000269385]
Chromobox protein homolog 8; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Synonyms: CBX8, CBX8p, hCBX8, C9J6K3, C9JM54 ...