DISEASES

Disease-gene associations mined from literature

Literature associating MFGE8 and topographical agnosia

MFGE8 [ENSP00000268150]

Lactadherin short form; Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction.

Synonyms:  MFGE8,  MFGE8p,  hMFGE8,  A0A087WUV5,  H0YKB5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM