DISEASES

Disease-gene associations mined from literature

Literature associating ADAM22 and hyperekplexia

ADAM22 [ENSP00000265727]

Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein . Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.

Synonyms:  ADAM22,  ADAM22p,  hADAM22,  E7EPF1,  E9PF78 ...

Linkouts:  STRING  Pharos  UniProt  OMIM