DISEASES

Disease-gene associations mined from literature

Literature associating CASP6 and thoracic cancer

CASP6 [ENSP00000265164]

Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death; Belongs to the peptidase C14A family.

Synonyms:  CASP6,  CASP6p,  hCASP6,  D6RBM3,  D6RHU3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM