DISEASES

Disease-gene associations mined from literature

Literature associating ICAM1 and parametritis

ICAM1 [ENSP00000264832]

Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins.

Synonyms:  ICAM1,  ICAM1p,  hICAM1,  A0A384MEK5,  E7ESS4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM