DISEASES

Disease-gene associations mined from literature

Literature associating KCNN2 and familial periodic paralysis

KCNN2 [ENSP00000264773]

Small conductance calcium-activated potassium channel protein 2; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin; Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily.

Synonyms:  KCNN2,  KCNN2p,  hKCNN2,  A0A0J9YW81,  A0A3F2YNY5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM