DISEASES

Disease-gene associations mined from literature

Literature associating MECOM and thrombocytopenia

MECOM [ENSP00000264674]

Histone-lysine N-methyltransferase MECOM; [Isoform 1]: Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis. ECO:0000269|PubMed:11568182, ECO:0000269|PubMed:15897867, ECO:0000269|PubMed:16462766, ECO:0000269|PubMed:19767769,

Synonyms:  MECOM,  A0A0C3SFZ7,  A0A1B0GXI8,  C9JU02,  E7EPY2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM