Literature associating IL11 and Langerhans-cell histiocytosis
IL11 [ENSP00000264563]
Interleukin-11; Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production . Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation . Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. ; Belongs to the IL-6 superfamily.
Synonyms: IL11, IL11p, hIL11, A8K3F7, K7ESD5 ...