DISEASES

Disease-gene associations mined from literature

Literature associating FGF2 and keratitis

FGF2 [ENSP00000264498]

Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 . Also acts as an integrin ligand which is required for FGF2 signaling . Binds to integrin ITGAV:ITGB3 . Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration . Functions as a potent mitogen in vitro . Can induce angiogenesis . ECO:0000269|PubMed:23469107, ECO:0000269|PubMed:28302677, ECO:0000269|PubMed:3732516, ECO:0000269|PubMed:3964259,

Synonyms:  FGF2,  FGF2p,  hFGF2,  A0A087WUF6,  A0A0A0MQV6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM