Literature associating FNIP2 and primary spontaneous pneumothorax
FNIP2 [ENSP00000264433]
Folliculin-interacting protein 2; Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1 . May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways . May regulate phosphorylation of RPS6KB1 .
Synonyms: FNIP2, FNIP2p, hFNIP2, D6RFH5, H0Y8F3 ...