DISEASES

Disease-gene associations mined from literature

Literature associating MECR and salivary gland cancer

MECR [ENSP00000263702]

Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Has a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16).

Synonyms:  MECR,  H3BM30,  Q9BV79,  H3BM30p,  hH3BM30 ...

Linkouts:  STRING  Pharos  UniProt  OMIM