DISEASES

Disease-gene associations mined from literature

Literature associating HIRA and Nezelof syndrome

HIRA [ENSP00000263208]

Protein HIRA; Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Synonyms:  H7C2A7,  P54198,  H7C2A7p,  hH7C2A7,  P54198p ...

Linkouts:  STRING  Pharos  UniProt