DISEASES

Disease-gene associations mined from literature

Literature associating GAB1 and Noonan syndrome with multiple lentigines

GAB1 [ENSP00000262995]

GRB2-associated-binding protein 1; Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway . ; Belongs to the GAB family.

Synonyms:  GAB1,  GAB1p,  hGAB1,  B7Z3B9,  D6RF42 ...

Linkouts:  STRING  Pharos  UniProt  OMIM