Literature associating MEOX2 and isolated cleft palate
MEOX2 [ENSP00000262041]
Homeobox protein MOX-2; Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner . May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Synonyms: MEOX2, MEOX2p, hMEOX2, P50222, P50222p ...