DISEASES

Disease-gene associations mined from literature

Literature associating PPP2R3C and holoprosencephaly 8

PPP2R3C [ENSP00000261475]

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; May regulate MCM3AP phosphorylation through phosphatase recruitment (By similarity). May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex . May play a role in the activation-induced cell death of B-cells (By similarity).

Synonyms:  PPP2R3C,  PPP2R3Cp,  hPPP2R3C,  A0A0C4DGK2,  G3V228 ...

Linkouts:  STRING  Pharos  UniProt