DISEASES

Disease-gene associations mined from literature

Literature associating MOCOS and prolidase deficiency

MOCOS [ENSP00000261326]

Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime. ; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.

Synonyms:  MOCOS,  Q96EN8,  Q96EN8p,  hQ96EN8,  2.8.1.9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM