DISEASES

Disease-gene associations mined from literature

Literature associating KIF23 and Noonan syndrome 5

KIF23 [ENSP00000260363]

Kinesin-like protein KIF23; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. ; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

Synonyms:  KIF23,  KIF23p,  hKIF23,  A0A2R8Y531,  A0A2U3TZL8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM