DISEASES

Disease-gene associations mined from literature

Literature associating FDX1 and maxillary sinus benign neoplasm

FDX1 [ENSP00000260270]

Adrenodoxin, mitochondrial; Essential for the synthesis of various steroid hormones . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783). Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity). ; Belongs to the adrenodoxin/putidaredoxin family.

Synonyms:  FDX1,  FDX1p,  hFDX1,  P10109,  P10109p ...

Linkouts:  STRING  Pharos  UniProt  OMIM