DISEASES

Disease-gene associations mined from literature

Literature associating ACTR3B and Noonan syndrome with multiple lentigines 1

ACTR3B [ENSP00000256001]

Actin-related protein 3B; Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.

Synonyms:  ACTR3B,  ACTR3Bp,  hACTR3B,  Q9P1U1,  Q9P1U1p ...

Linkouts:  STRING  Pharos  UniProt