DISEASES

Disease-gene associations mined from literature

Literature associating HSPBP1 and Sjogren-Larsson syndrome

HSPBP1 [ENSP00000255631]

Hsp70-binding protein 1; Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Synonyms:  HSPBP1,  HSPBP1p,  hHSPBP1,  K7EKM6,  K7EL16 ...

Linkouts:  STRING  Pharos  UniProt  OMIM