DISEASES

Disease-gene associations mined from literature

Literature associating SERPINF1 and retinal detachment

SERPINF1 [ENSP00000254722]

Pigment epithelium-derived factor; Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Synonyms:  SERPINF1,  A0A140VKF3,  I3L107,  I3L1U4,  I3L2R7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM