DISEASES

Disease-gene associations mined from literature

Literature associating EPO and uremia

EPO [ENSP00000252723]

Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. ; Belongs to the EPO/TPO family.

Synonyms:  EPO,  G9JKG7,  P01588,  G9JKG7p,  hG9JKG7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM