Literature associating RRM2B and sensorineural hearing loss
RRM2B [ENSP00000251810]
Ribonucleoside-diphosphate reductase subunit M2 B; Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage. ; Belongs to the ribonucleoside diphosphate reductase small chain family.
Synonyms: RRM2B, RRM2Bp, hRRM2B, A0A0C4DGZ6, E5RG52 ...