Literature associating FLRT1 and spastic ataxia 3
FLRT1 [ENSP00000246841]
Leucine-rich repeat transmembrane protein FLRT1; Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases. Promotes neurite outgrowth via FGFR1-mediated activation of downstream MAP kinases. Promotes an increase both in neurite number and in neurite length. May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3.
Synonyms: FLRT1, FLRT1p, hFLRT1, Q9NZU1, Q9NZU1p ...