DISEASES

Disease-gene associations mined from literature

Literature associating TNFSF10 and bone disease

TNFSF10 [ENSP00000241261]

Tumor necrosis factor ligand superfamily member 10; Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG . Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. ; Belongs to the tumor necrosis factor family.

Synonyms:  TNFSF10,  TNFSF10p,  hTNFSF10,  H7C246,  P50591 ...

Linkouts:  STRING  Pharos  UniProt  OMIM