Literature associating HAND1 and tetralogy of Fallot
HAND1 [ENSP00000231121]
Heart- and neural crest derivatives-expressed protein 1; Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis (By similarity). Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity). Acts as a transcriptional repressor of SOX15 (By similarity). In the adult, could be required for ongoing expression of cardiac-specific genes .
Synonyms: HAND1, HAND1p, hHAND1, O96004, O96004p ...