DISEASES

Disease-gene associations mined from literature

Literature associating SULT1E1 and pericardium disease

SULT1E1 [ENSP00000226444]

Sulfotransferase 1E1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone (PubMed:7779757, PubMed:11884392, PubMed:11006110). Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesterol and xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency . Does not sulfonate cortisol, testosterone and dopamine .

Synonyms:  SULT1E1,  SULT1E1p,  hSULT1E1,  P49888,  Q53X91 ...

Linkouts:  STRING  Pharos  UniProt  OMIM