DISEASES

Disease-gene associations mined from literature

Literature associating VCL and keratosis follicularis

VCL [ENSP00000211998]

Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family.

Synonyms:  VCL,  A0A024QZN4,  A0A096LPE1,  HEL114,  P18206 ...

Linkouts:  STRING  Pharos  UniProt  OMIM