DISEASES

Disease-gene associations mined from literature

Literature associating CHRD and holoprosencephaly 4

CHRD [ENSP00000204604]

Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family.

Synonyms:  CHRD,  E7ESX1,  Q9H2X0,  E7ESX1p,  hE7ESX1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM